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SOCS1 counteracts ROS-mediated survival signals and promotes apoptosis by modulating cell cycle to increase radiosensitivity of colorectal cancer cells

As negative regulators of cytokine signaling pathways, suppressors of cytokine signaling (SOCS) proteins have been reported to possess both pro-tumor and anti-tumor functions. Our recent studies have demonstrated suppressive effects of SOCS1 on epithelial to mesenchymal signaling in colorectal cance...

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Detalles Bibliográficos
Autores principales: Ryu, Ji-Yoon, Oh, Jiyoung, Kim, Su-Min, Kim, Won-Gi, Jeong, Hana, Ahn, Shin-Ae, Kim, Seol-Hee, Jang, Ji-Young, Yoo, Byong Chul, Kim, Chul Woo, Lee, Choong-Eun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9058468/
https://www.ncbi.nlm.nih.gov/pubmed/35321782
http://dx.doi.org/10.5483/BMBRep.2022.55.4.191