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K27‐linked ubiquitylation promotes p97 substrate processing and is essential for cell proliferation
Conjugation of ubiquitin (Ub) to numerous substrate proteins regulates virtually all cellular processes. Eight distinct ubiquitin polymer linkages specifying different functional outcomes are generated in cells. However, the roles of some atypical poly‐ubiquitin topologies, in particular linkages vi...
Autores principales: | Shearer, Robert F, Typas, Dimitris, Coscia, Fabian, Schovsbo, Sofie, Kruse, Thomas, Mund, Andreas, Mailand, Niels |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9058539/ https://www.ncbi.nlm.nih.gov/pubmed/35349166 http://dx.doi.org/10.15252/embj.2021110145 |
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