Structure of the RZZ complex and molecular basis of Spindly‐driven corona assembly at human kinetochores

In metazoans, a ≈1 megadalton (MDa) multiprotein complex comprising the dynein–dynactin adaptor Spindly and the ROD–Zwilch–ZW10 (RZZ) complex is the building block of a fibrous biopolymer, the kinetochore fibrous corona. The corona assembles on mitotic kinetochores to promote microtubule capture and...

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Detalles Bibliográficos
Autores principales: Raisch, Tobias, Ciossani, Giuseppe, d’Amico, Ennio, Cmentowski, Verena, Carmignani, Sara, Maffini, Stefano, Merino, Felipe, Wohlgemuth, Sabine, Vetter, Ingrid R, Raunser, Stefan, Musacchio, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9058546/
https://www.ncbi.nlm.nih.gov/pubmed/35373361
http://dx.doi.org/10.15252/embj.2021110411

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