Design, synthesis and bioevaluation of novel 6-substituted aminoindazole derivatives as anticancer agents

In the present study, a series of 6-substituted aminoindazole derivatives were designed, synthesized, and evaluated for bio-activities. The compounds were initially designed as indoleamine 2,3-dioxygenase 1 (IDO1) inhibitors based on the structural feature of five IDO1 inhibitors, which are currentl...

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Detalles Bibliográficos
Autores principales: Hoang, Ngo Xuan, Hoang, Van-Hai, Luu, Thi-Thu-Trang, Luu, Hung N., Ngo, Thien, Van Hieu, Duong, Long, Nguyen Huu, Anh, Le Viet, Ngo, Son Tung, Nguyen, Yen Thi Kim, Han, Byung Woo, Nguyen, Thanh Xuan, Hai, Dinh Thi Thanh, Hien, Tran Thi Thu, Tran, Phuong-Thao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9058813/
https://www.ncbi.nlm.nih.gov/pubmed/35516257
http://dx.doi.org/10.1039/d0ra09112j

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