A hybrid approach for identifying drug repurposing candidates and their mechanisms: An interview with Vanessa Lage-Rupprecht and two co-authors

Senior researcher Vanessa Lage-Rupprecht and two collaborators talk about what data science means to them and illustrate how they managed to create a data and lab coexistence in their drug-repurposing project, which was recently published in Patterns. In this article, they have developed a drug-targ...

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Detalles Bibliográficos
Autores principales: Lage-Rupprecht, Vanessa, Schultz, Bruce, Namysl, Marcin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
People of Data
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9058869/
https://www.ncbi.nlm.nih.gov/pubmed/35510189
http://dx.doi.org/10.1016/j.patter.2022.100466
Descripción
Sumario:Senior researcher Vanessa Lage-Rupprecht and two collaborators talk about what data science means to them and illustrate how they managed to create a data and lab coexistence in their drug-repurposing project, which was recently published in Patterns. In this article, they have developed a drug-target-mechanism-oriented data model, Human Brain PHARMACOME, and have presented it as a resource to the community.

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