Nanostructured polyvinylpyrrolidone-curcumin conjugates allowed for kidney-targeted treatment of cisplatin induced acute kidney injury

Acute kidney injury (AKI) leads to unacceptably high mortality due to difficulties in timely intervention and less efficient renal delivery of therapeutic drugs. Here, a series of polyvinylpyrrolidone (PVP)-curcumin nanoparticles (PCurNP) are designed to meet the renal excretion threshold (∼45 kDa),...

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Detalles Bibliográficos
Autores principales: Wei, Hao, Jiang, Dawei, Yu, Bo, Ni, Dalong, Li, Mengting, Long, Yin, Ellison, Paul A., Siamof, Cerise M., Cheng, Liang, Barnhart, Todd E., Im, Hyung-Jun, Yu, Faquan, Lan, Xiaoli, Zhu, Xiaohua, He, Qianjun, Cai, Weibo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9058893/
https://www.ncbi.nlm.nih.gov/pubmed/35574055
http://dx.doi.org/10.1016/j.bioactmat.2022.04.006

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