Characterizing kinase intergenic-breakpoint rearrangements in a large-scale lung cancer population and real-world clinical outcomes

BACKGROUND: Kinase gene fusions are strong driver mutations in neoplasia; however, kinase intergenic-breakpoint rearrangements (IGRs) confound the detection of such fusions and of targeted treatments. We aim to provide an overview of kinase IGRs in a large lung cancer cohort and examine real-world s...

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Detalles Bibliográficos
Autores principales: Yao, Y., Yu, Z., Ma, Y., Ou, Q., Wu, X., Lu, D., Li, X.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9058911/
https://www.ncbi.nlm.nih.gov/pubmed/35305401
http://dx.doi.org/10.1016/j.esmoop.2022.100405

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