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scTenifoldKnk: An efficient virtual knockout tool for gene function predictions via single-cell gene regulatory network perturbation

Gene knockout (KO) experiments are a proven, powerful approach for studying gene function. However, systematic KO experiments targeting a large number of genes are usually prohibitive due to the limit of experimental and animal resources. Here, we present scTenifoldKnk, an efficient virtual KO tool...

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Detalles Bibliográficos
Autores principales:	Osorio, Daniel, Zhong, Yan, Li, Guanxun, Xu, Qian, Yang, Yongjian, Tian, Yanan, Chapkin, Robert S., Huang, Jianhua Z., Cai, James J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9058914/ https://www.ncbi.nlm.nih.gov/pubmed/35510185 http://dx.doi.org/10.1016/j.patter.2022.100434

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