Oncogenic Vav1-Myo1f induces therapeutically targetable macrophage-rich tumor microenvironment in peripheral T cell lymphoma

Peripheral T cell lymphoma not otherwise specified (PTCL-NOS) comprises heterogeneous lymphoid malignancies characterized by pleomorphic lymphocytes and variable inflammatory cell-rich tumor microenvironment. Genetic drivers in PTCL-NOS include genomic alterations affecting the VAV1 oncogene; howeve...

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Detalles Bibliográficos
Autores principales: Cortes, Jose R., Filip, Ioan, Albero, Robert, Patiño-Galindo, Juan A., Quinn, S. Aidan, Lin, Wen-Hsuan W., Laurent, Anouchka P., Shih, Bobby B., Brown, Jessie A., Cooke, Anisha J., Mackey, Adam, Einson, Jonah, Zairis, Sakellarios, Rivas-Delgado, Alfredo, Antonella Laginestra, Maria, Pileri, Stefano, Campo, Elias, Bhagat, Govind, Ferrando, Adolfo A., Rabadan, Raul, Palomero, Teresa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9059228/
https://www.ncbi.nlm.nih.gov/pubmed/35443168
http://dx.doi.org/10.1016/j.celrep.2022.110695

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