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Experimental and theoretical investigation of cyclometallated platinum(ii) complex containing adamantanemethylcyanamide and 1,4-naphthoquinone derivative as ligands: synthesis, characterization, interacting with guanine and cytotoxic activity

A new cyclometallated platinum(ii) complex with 1-adamantanemethylcyanamide (1-ADpcydH) and 2-[amino(2-phenylpyridine)]-1,4-naphthoquinone (1,4-NQ) ligands with the formula cis-Pt(1,4-NQ)(1-ADpcyd)(H(2)O) was synthesized and fully characterized. Cellular uptake, DNA platination, and cytotoxicity aga...

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Detalles Bibliográficos
Autores principales: Tabrizi, Leila, Zouchoune, Bachir, Zaiter, Abdallah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9059274/
https://www.ncbi.nlm.nih.gov/pubmed/35521610
http://dx.doi.org/10.1039/c8ra08739c

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