Light-triggered hydrophilic drug release from liposomes through removal of a photolabile protecting group

The antibiotic penicillin G cannot be completely incorporated into hydrophobic lipid-membranes owing to its hydrophilicity. Through modification with a hydrophobic and photolabile protecting group, penicillin G was effectively incorporated into liposomes and released by photoirradiation at 365 nm.

Detalles Bibliográficos
Autores principales: Goto, Yuya, Ueda, Masafumi, Sugikawa, Kouta, Yasuhara, Kazuma, Ikeda, Atsushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9059325/
https://www.ncbi.nlm.nih.gov/pubmed/35521599
http://dx.doi.org/10.1039/c8ra08584f
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author Goto, Yuya
Ueda, Masafumi
Sugikawa, Kouta
Yasuhara, Kazuma
Ikeda, Atsushi
author_facet Goto, Yuya
Ueda, Masafumi
Sugikawa, Kouta
Yasuhara, Kazuma
Ikeda, Atsushi
author_sort Goto, Yuya
collection PubMed
description The antibiotic penicillin G cannot be completely incorporated into hydrophobic lipid-membranes owing to its hydrophilicity. Through modification with a hydrophobic and photolabile protecting group, penicillin G was effectively incorporated into liposomes and released by photoirradiation at 365 nm.
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spelling pubmed-90593252022-05-04 Light-triggered hydrophilic drug release from liposomes through removal of a photolabile protecting group Goto, Yuya Ueda, Masafumi Sugikawa, Kouta Yasuhara, Kazuma Ikeda, Atsushi RSC Adv Chemistry The antibiotic penicillin G cannot be completely incorporated into hydrophobic lipid-membranes owing to its hydrophilicity. Through modification with a hydrophobic and photolabile protecting group, penicillin G was effectively incorporated into liposomes and released by photoirradiation at 365 nm. The Royal Society of Chemistry 2018-12-21 /pmc/articles/PMC9059325/ /pubmed/35521599 http://dx.doi.org/10.1039/c8ra08584f Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Chemistry
Goto, Yuya
Ueda, Masafumi
Sugikawa, Kouta
Yasuhara, Kazuma
Ikeda, Atsushi
Light-triggered hydrophilic drug release from liposomes through removal of a photolabile protecting group
title Light-triggered hydrophilic drug release from liposomes through removal of a photolabile protecting group
title_full Light-triggered hydrophilic drug release from liposomes through removal of a photolabile protecting group
title_fullStr Light-triggered hydrophilic drug release from liposomes through removal of a photolabile protecting group
title_full_unstemmed Light-triggered hydrophilic drug release from liposomes through removal of a photolabile protecting group
title_short Light-triggered hydrophilic drug release from liposomes through removal of a photolabile protecting group
title_sort light-triggered hydrophilic drug release from liposomes through removal of a photolabile protecting group
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9059325/
https://www.ncbi.nlm.nih.gov/pubmed/35521599
http://dx.doi.org/10.1039/c8ra08584f
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