Determinants of the willingness to get the third COVID-19 vaccine dose among health care workers

OBJECTIVE: To characterize the willingness to get the third COVID-19 vaccine dose among health care workers (HCWs). METHODS: A cross-sectional study using a self-administered questionnaire proposed on a voluntary basis to all HCWs of a French teaching hospital in October and November 2021. RESULTS: Of 1,655 HCWs who completed the questionnaire, 64.2% were willing to receive the third dose, 20.1% were hesitant, and 15.7% were reluctant. On multivariate analysis, older age (P < 0.0001), medical and executive staff, willingness to receive the flu vaccine (OR = 5.72 [4.24–7.64]), previous vaccine scheme with ChAdOx1 nCoV-19 (AstraZeneca) (OR = 2.13 [1.58–2.87]), and history of COVID-19 with a complete COVID-19 vaccine scheme (OR = 2.77 [1.04–7.41]) were independent predictors of HCWs’ willingness to get the third dose. CONCLUSIONS: One third of HCWs were hesitant or opposed to a third COVID-19 vaccine dose. Better knowledge of determinants of the willingness to get this third dose may improve communication and vaccine strategy.