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Tetra-fluorinated aromatic azide for highly efficient bioconjugation in living cells
We developed a fast strain-promoted azide–alkyne cycloaddition reaction (SPAAC) by tetra-fluorinated aromatic azide with a kinetic constant of 3.60 M(−1) s(−1), which is among the fastest SPAAC ligations reported so far. We successfully employed the reaction for covalent labelling of proteins with h...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society of Chemistry
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9059488/ https://www.ncbi.nlm.nih.gov/pubmed/35521584 http://dx.doi.org/10.1039/c8ra09303b |