Cargando…
Secondary metabolites (SMs) of Isaria cicadae and Isaria tenuipes
Both Isaria cicadae and Isaria tenuipes are important entomopathogenic fungi used in health foods and traditional herbal medicines in East Asia. However, the safety concerns for both fungal species have been attracting significant attention. Thus, surveying their secondary metabolites (SMs) will be...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9059538/ https://www.ncbi.nlm.nih.gov/pubmed/35521576 http://dx.doi.org/10.1039/c8ra09039d |
_version_ | 1784698333606969344 |
---|---|
author | Zhang, Xiaofeng Hu, Qiongbo Weng, Qunfang |
author_facet | Zhang, Xiaofeng Hu, Qiongbo Weng, Qunfang |
author_sort | Zhang, Xiaofeng |
collection | PubMed |
description | Both Isaria cicadae and Isaria tenuipes are important entomopathogenic fungi used in health foods and traditional herbal medicines in East Asia. However, the safety concerns for both fungal species have been attracting significant attention. Thus, surveying their secondary metabolites (SMs) will be beneficial to improving the safety of their fungal products. In the case of I. cicadae, its SMs mainly include nucleosides, amino acids, beauvericins, myriocin, and oosporein. In contrast, trichothecene derivatives, isariotins, cyclopenta benzopyrans and PKs, are found in the case of I. tenuipes. Among them, beauvericins, myriocin, oosporein and many trichothecene derivatives are toxic compounds. The toxicity and side effects of the fungal products may be related to these SMs. Thus, to ensure the safety of fungal products, the residues standards of SMs need to be reported. Furthermore, methods for the detection of their SMs and biological identification of their strains must be considered. This review gives new insight into the secondary metabolites of medical and edible fungi. |
format | Online Article Text |
id | pubmed-9059538 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | The Royal Society of Chemistry |
record_format | MEDLINE/PubMed |
spelling | pubmed-90595382022-05-04 Secondary metabolites (SMs) of Isaria cicadae and Isaria tenuipes Zhang, Xiaofeng Hu, Qiongbo Weng, Qunfang RSC Adv Chemistry Both Isaria cicadae and Isaria tenuipes are important entomopathogenic fungi used in health foods and traditional herbal medicines in East Asia. However, the safety concerns for both fungal species have been attracting significant attention. Thus, surveying their secondary metabolites (SMs) will be beneficial to improving the safety of their fungal products. In the case of I. cicadae, its SMs mainly include nucleosides, amino acids, beauvericins, myriocin, and oosporein. In contrast, trichothecene derivatives, isariotins, cyclopenta benzopyrans and PKs, are found in the case of I. tenuipes. Among them, beauvericins, myriocin, oosporein and many trichothecene derivatives are toxic compounds. The toxicity and side effects of the fungal products may be related to these SMs. Thus, to ensure the safety of fungal products, the residues standards of SMs need to be reported. Furthermore, methods for the detection of their SMs and biological identification of their strains must be considered. This review gives new insight into the secondary metabolites of medical and edible fungi. The Royal Society of Chemistry 2018-12-21 /pmc/articles/PMC9059538/ /pubmed/35521576 http://dx.doi.org/10.1039/c8ra09039d Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/ |
spellingShingle | Chemistry Zhang, Xiaofeng Hu, Qiongbo Weng, Qunfang Secondary metabolites (SMs) of Isaria cicadae and Isaria tenuipes |
title | Secondary metabolites (SMs) of Isaria cicadae and Isaria tenuipes |
title_full | Secondary metabolites (SMs) of Isaria cicadae and Isaria tenuipes |
title_fullStr | Secondary metabolites (SMs) of Isaria cicadae and Isaria tenuipes |
title_full_unstemmed | Secondary metabolites (SMs) of Isaria cicadae and Isaria tenuipes |
title_short | Secondary metabolites (SMs) of Isaria cicadae and Isaria tenuipes |
title_sort | secondary metabolites (sms) of isaria cicadae and isaria tenuipes |
topic | Chemistry |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9059538/ https://www.ncbi.nlm.nih.gov/pubmed/35521576 http://dx.doi.org/10.1039/c8ra09039d |
work_keys_str_mv | AT zhangxiaofeng secondarymetabolitessmsofisariacicadaeandisariatenuipes AT huqiongbo secondarymetabolitessmsofisariacicadaeandisariatenuipes AT wengqunfang secondarymetabolitessmsofisariacicadaeandisariatenuipes |