Formal [4 + 1] cycloaddition of in situ generated 1,2-diaza-1,3-dienes with diazo esters: facile approaches to dihydropyrazoles containing a quaternary center

A Cu(ii)/bisoxazoline ligand-promoted formal [4 + 1] cycloaddition of diazo esters with azoalkenes formed in situ has been developed. This strategy provides a potential protocol for the construction of dihydropyrazoles containing a quaternary center with good to excellent yields.

Detalles Bibliográficos
Autores principales: Chen, Bo, Chu, Wen-Dao, Liu, Quan-Zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9059575/
https://www.ncbi.nlm.nih.gov/pubmed/35518004
http://dx.doi.org/10.1039/c8ra08909d
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author Chen, Bo
Chu, Wen-Dao
Liu, Quan-Zhong
author_facet Chen, Bo
Chu, Wen-Dao
Liu, Quan-Zhong
author_sort Chen, Bo
collection PubMed
description A Cu(ii)/bisoxazoline ligand-promoted formal [4 + 1] cycloaddition of diazo esters with azoalkenes formed in situ has been developed. This strategy provides a potential protocol for the construction of dihydropyrazoles containing a quaternary center with good to excellent yields.
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spelling pubmed-90595752022-05-04 Formal [4 + 1] cycloaddition of in situ generated 1,2-diaza-1,3-dienes with diazo esters: facile approaches to dihydropyrazoles containing a quaternary center Chen, Bo Chu, Wen-Dao Liu, Quan-Zhong RSC Adv Chemistry A Cu(ii)/bisoxazoline ligand-promoted formal [4 + 1] cycloaddition of diazo esters with azoalkenes formed in situ has been developed. This strategy provides a potential protocol for the construction of dihydropyrazoles containing a quaternary center with good to excellent yields. The Royal Society of Chemistry 2019-01-11 /pmc/articles/PMC9059575/ /pubmed/35518004 http://dx.doi.org/10.1039/c8ra08909d Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Chemistry
Chen, Bo
Chu, Wen-Dao
Liu, Quan-Zhong
Formal [4 + 1] cycloaddition of in situ generated 1,2-diaza-1,3-dienes with diazo esters: facile approaches to dihydropyrazoles containing a quaternary center
title Formal [4 + 1] cycloaddition of in situ generated 1,2-diaza-1,3-dienes with diazo esters: facile approaches to dihydropyrazoles containing a quaternary center
title_full Formal [4 + 1] cycloaddition of in situ generated 1,2-diaza-1,3-dienes with diazo esters: facile approaches to dihydropyrazoles containing a quaternary center
title_fullStr Formal [4 + 1] cycloaddition of in situ generated 1,2-diaza-1,3-dienes with diazo esters: facile approaches to dihydropyrazoles containing a quaternary center
title_full_unstemmed Formal [4 + 1] cycloaddition of in situ generated 1,2-diaza-1,3-dienes with diazo esters: facile approaches to dihydropyrazoles containing a quaternary center
title_short Formal [4 + 1] cycloaddition of in situ generated 1,2-diaza-1,3-dienes with diazo esters: facile approaches to dihydropyrazoles containing a quaternary center
title_sort formal [4 + 1] cycloaddition of in situ generated 1,2-diaza-1,3-dienes with diazo esters: facile approaches to dihydropyrazoles containing a quaternary center
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9059575/
https://www.ncbi.nlm.nih.gov/pubmed/35518004
http://dx.doi.org/10.1039/c8ra08909d
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AT liuquanzhong formal41cycloadditionofinsitugenerated12diaza13dieneswithdiazoestersfacileapproachestodihydropyrazolescontainingaquaternarycenter

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