Neutrophil-mediated and low density lipoprotein receptor-mediated dual-targeting nanoformulation enhances brain accumulation of scutellarin and exerts neuroprotective effects against ischemic stroke

Delivery of poorly permeable drugs across the blood-brain barrier (BBB) is a great challenge in the treatment of ischemic stroke. In order to construct a suitable delivery system for this purpose, we developed a dual-targeting nanoformulation to transfer therapeutic agents targeting the inflammatory...

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Detalles Bibliográficos
Autores principales: Dang, Yanxin, An, Chiying, Li, Yutao, Han, Dandan, Liu, Xin, Zhang, Fengming, Xu, Yuan, Zhong, Haijing, Karim Khan, Mewand Khan, Zou, Fengjuan, Sun, Xiaojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9059646/
https://www.ncbi.nlm.nih.gov/pubmed/35518053
http://dx.doi.org/10.1039/c8ra06688d

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9059646/
https://www.ncbi.nlm.nih.gov/pubmed/35518053
http://dx.doi.org/10.1039/c8ra06688d

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