Discovery of novel elongator protein 2 inhibitors by compound library screening using surface plasmon resonance

Tumour necrosis factor-α (TNF-α) is a pleiotropic cytokine that becomes elevated in chronic inflammatory states, including slowing down osteogenic differentiation, which leads to bone dysplasia in long-term inflammatory microenvironments. The elongator complex plays a role in gene regulation and ass...

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Detalles Bibliográficos
Autores principales: Xu, Chang-Peng, Qi, Yong, Cui, Zhuang, Yang, Ya-Jun, Wang, Jian, Hu, Yan-Jun, Yu, Bin, Wang, Fa-Zheng, Yang, Qing-Po, Sun, Hong-Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9059734/
https://www.ncbi.nlm.nih.gov/pubmed/35518050
http://dx.doi.org/10.1039/c8ra09640f

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