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Acute myeloid leukemia with an MN1-ETV6 fusion in a young child with Down syndrome

Myeloid leukemia of Down syndrome (ML-DS) in young children is associated with distinct clinical and biological features and is typically initiated with oncogenic mutations in the X-linked megakaryocytic transcription factor GATA1. Here we present a 3-yr-old child with DS diagnosed with acute myeloi...

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Detalles Bibliográficos
Autores principales: Rosenzweig, Jaclyn, Pillai, Pallavi M., Prockop, Susan, Benayed, Ryma, Eidenschink Brodersen, Lisa, Najfeld, Vesna, Loken, Michael R., Zhang, Yanming, Shukla, Neerav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9059786/
https://www.ncbi.nlm.nih.gov/pubmed/35483876
http://dx.doi.org/10.1101/mcs.a006167

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