Whole-genome and transcriptome analysis of advanced adrenocortical cancer highlights multiple alterations affecting epigenome and DNA repair pathways

Adrenocortical cancer (ACC) is a rare cancer of the adrenal gland. Several driver mutations have been identified in both primary and metastatic ACCs, but the therapeutic options are still limited. We performed whole-genome and transcriptome sequencing on seven patients with metastatic ACC. Integrati...

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Detalles Bibliográficos
Autores principales: Lavoie, Jean-Michel, Csizmok, Veronika, Williamson, Laura M., Culibrk, Luka, Wang, Gang, Marra, Marco A., Laskin, Janessa, Jones, Steven J.M., Renouf, Daniel J., Kollmannsberger, Christian K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2022
Materias:
Research Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9059790/
https://www.ncbi.nlm.nih.gov/pubmed/35483882
http://dx.doi.org/10.1101/mcs.a006148

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