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Development of a hybrid peptide dendrimer micellar carrier system and its application in the reformulation of a hydrophobic therapeutic agent derived from traditional Chinese medicine

The discovery that a cane toad poison-derived steroid, bufalin can significantly impact cancer cell proliferation supports its potential use in cancer therapy. However, its poor aqueous solubility and tissue deposition characteristics hamper its broader application as an anticancer therapeutic agent...

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Detalles Bibliográficos
Autores principales: Jing, Jing, Tupally, Karnaker R., Kokil, Ganesh R., Qu, Zhi, Chen, Sibao, Parekh, Harendra S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9059851/
https://www.ncbi.nlm.nih.gov/pubmed/35520530
http://dx.doi.org/10.1039/c8ra09606f