Ultrasensitive strips for the quadruple detection of nitrofuran metabolite residues

In this biosensor system, metabolite residues were derived by using a previous B-CBA synthesis method to label a biotin moiety for enrichment by streptavidin coated magnetic beads. Antibodies specific for derivatives were conjugated with carboxyl-modified barcode DNAs which were used as templates fo...

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Detalles Bibliográficos
Autores principales: Wu, Wei, Sun, Ning, Zhu, Simin, Li, Xiaomei, Chen, Jitao, Liu, Chunzhao, Fang, Zhiyuan, Yang, Qingli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9059960/
https://www.ncbi.nlm.nih.gov/pubmed/35520510
http://dx.doi.org/10.1039/c8ra10589h
Descripción
Sumario:In this biosensor system, metabolite residues were derived by using a previous B-CBA synthesis method to label a biotin moiety for enrichment by streptavidin coated magnetic beads. Antibodies specific for derivatives were conjugated with carboxyl-modified barcode DNAs which were used as templates for strand displacement amplification (SDA). The assay can detect trace levels of 7.20 ppt of SEM, 11.58 ppt of AHD, 7.24 ppt of AOZ and 2.31 ppt of AMOZ, respectively.

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