Cargando…

CD8αα(+)T cells exert a pro‐inflammatory role in patients with psoriasis

BACKGROUND: Psoriasis is a common chronic inflammatory disease caused by excessive activation of CD4(+)T cells, including Th17, Th1 and Th22. The role of CD8(+)T cells in psoriasis pathogenesis remains poorly understood. AIM: To identify the phenotype of CD8(+)T cells in patients with psoriasis and...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Y. Y., Lin, Y. T., Wang, L., Sun, X. W., Dang, E. L., Xue, K., Zhang, W. G., Zhang, K. M., Wang, G., Li, B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9060015/ https://www.ncbi.nlm.nih.gov/pubmed/35663772 http://dx.doi.org/10.1002/ski2.64

Ejemplares similares

WNT5A transforms intestinal CD8αα(+) IELs into an unconventional phenotype with pro-inflammatory features
por: Zhao, Di, et al.
Publicado: (2015)

Development and function of natural TCR(+) CD8αα(+) intraepithelial lymphocytes
por: Gui, Yuanyuan, et al.
Publicado: (2022)

CD4CD8αα IELs: They Have Something to Say
por: Zhou, Chao, et al.
Publicado: (2019)

Intracellular metabolic adaptation of intraepithelial CD4(+)CD8αα(+) T lymphocytes
por: Harada, Yosuke, et al.
Publicado: (2022)

Control of CD8αα intestinal intraepithelial lymphocyte development by TGF-β
por: Konkel, Joanne E., et al.
Publicado: (2011)

The first crystal structure of CD8αα from a cartilaginous fish
por: Jia, Zhao, et al.
Publicado: (2023)

GPR18 is required for a normal CD8αα intestinal intraepithelial lymphocyte compartment
por: Wang, Xiaoming, et al.
Publicado: (2014)

Identification and Regulation of TCRαβ(+)CD8αα(+) Intraepithelial Lymphocytes in Murine Oral Mucosa
por: Wu, Ruiqing, et al.
Publicado: (2020)

Lineage re-commitment of CD4CD8αα intraepithelial lymphocytes in the gut
por: Park, Yunji, et al.
Publicado: (2016)

CD8αα(+) Intraepithelial Lymphocytes Arise from Two Major Thymic Precursors
por: Ruscher, Roland, et al.
Publicado: (2017)

TGF-β controls development of TCRγδ(+)CD8αα(+) intestinal intraepithelial lymphocytes
por: Han, Jiajia, et al.
Publicado: (2023)

Innate CD8αα(+) lymphocytes enhance anti‐CD40 antibody‐mediated colitis in mice
por: Kumar, Aaram A., et al.
Publicado: (2017)

CD8αα Expression Marks Terminally Differentiated Human CD8+ T Cells Expanded in Chronic Viral Infection
por: Walker, L. J., et al.
Publicado: (2013)

The histone demethylase Kdm6b regulates the maturation and cytotoxicity of TCRαβ(+)CD8αα(+) intestinal intraepithelial lymphocytes
por: Zhang, Haohao, et al.
Publicado: (2022)

Microbiota-Specific CD4CD8αα Tregs: Role in Intestinal Immune Homeostasis and Implications for IBD
por: Sarrabayrouse, Guillaume, et al.
Publicado: (2015)

Immune Surveillance by CD8αα(+) Skin Resident T Cells in Human Herpesvirus Infection
por: Zhu, Jia, et al.
Publicado: (2013)

Chemokine receptor CCR9 suppresses the differentiation of CD4(+)CD8αα(+) intraepithelial T cells in the gut
por: Li, Can, et al.
Publicado: (2022)

Downregulation of chemokine receptor 9 facilitates CD4(+)CD8αα(+) intraepithelial lymphocyte development
por: Ono, Keiko, et al.
Publicado: (2023)

Non-canonicaly recruited TCRαβCD8αα IELs recognize microbial antigens
por: Wojciech, Lukasz, et al.
Publicado: (2018)

In situ differentiation of CD8αα Τ cells from CD4 T cells in peripheral lymphoid tissues
por: Nambu, Yukiko, et al.
Publicado: (2012)

Runx3d controls the abundance and functional differentiation of CD4(+)CD8αα(+) intraepithelial T cells
por: Li, Can, et al.
Publicado: (2023)

Limitations of the ABEGO-based backbone design: ambiguity between αα-corner and αα-hairpin
por: Sakuma, Koya
Publicado: (2021)

Innate CD8αα(+) cells promote ILC1-like intraepithelial lymphocyte homeostasis and intestinal inflammation
por: Nazmi, Ali, et al.
Publicado: (2019)

The pedigree analysis and prenatal diagnosis of Hong Kongαα Thalassemia and the sequence analysis of Hong Kongαα Allele
por: Wang, Wenjuan, et al.
Publicado: (2020)

Thymic progenitors of TCRαβ(+) CD8αα intestinal intraepithelial lymphocytes require RasGRP1 for development
por: Golec, Dominic P., et al.
Publicado: (2017)

CD4CD8αα Lymphocytes, A Novel Human Regulatory T Cell Subset Induced by Colonic Bacteria and Deficient in Patients with Inflammatory Bowel Disease
por: Sarrabayrouse, Guillaume, et al.
Publicado: (2014)

Peripheral blood CD8αα(+)CD11c(+)MHC(−)II(+)CD3- cells attenuate autoimmune glomerulonephritis in rats
por: Wu, Jean, et al.
Publicado: (2013)

Protocol to isolate and enrich mouse splenic naive CD4(+) T cells for in vitro CD4(+)CD8αα(+) cell induction
por: Harada, Yosuke, et al.
Publicado: (2022)

The Combination of CD8αα and Peptide-MHC-I in a Face-to-Face Mode Promotes Chicken γδT Cells Response
por: Liu, Yanjie, et al.
Publicado: (2020)

Niche-specific MHC II and PD-L1 regulate CD4(+)CD8αα(+) intraepithelial lymphocyte differentiation
por: Moon, Sookjin, et al.
Publicado: (2021)

Intestinal CD8αα IELs derived from two distinct thymic precursors have staggered ontogeny
por: Ruscher, Roland, et al.
Publicado: (2020)

Dominant Negative FADD/MORT1 Inhibits the Development of Intestinal Intraepithelial Lymphocytes With a Marked Defect on CD8αα+TCRγδ+ T Cells
por: Zhang, Xuerui, et al.
Publicado: (2018)

Increased TCR signal strength in DN thymocytes promotes development of gut TCRαβ((+))CD8αα((+)) intraepithelial lymphocytes
por: Grandjean, Capucine L., et al.
Publicado: (2017)

The structural basis of chicken, swine and bovine CD8αα dimers provides insight into the co-evolution with MHC I in endotherm species
por: Liu, Yanjie, et al.
Publicado: (2016)

Ly49E Expression on CD8αα-Expressing Intestinal Intraepithelial Lymphocytes Plays No Detectable Role in the Development and Progression of Experimentally Induced Inflammatory Bowel Diseases
por: Van Acker, Aline, et al.
Publicado: (2014)

Correction: Ly49E Expression on CD8αα-Expressing Intestinal Intraepithelial Lymphocytes Plays No Detectable Role in the Development and Progression of Experimentally Induced Inflammatory Bowel Diseases
Publicado: (2015)

Human thymic putative CD8αα precursors exhibit a biased TCR repertoire in single cell AIRR-seq
por: Heimli, Marte, et al.
Publicado: (2023)

Regulation of membrane phospholipid asymmetry by Notch-mediated flippase expression controls the number of intraepithelial TCRαβ(+)CD8αα(+) T cells
por: Ishifune, Chieko, et al.
Publicado: (2019)

Trimodal single-cell profiling reveals a novel pediatric CD8αα(+) T cell subset and broad age-related molecular reprogramming across the T cell compartment
por: Thomson, Zachary, et al.
Publicado: (2023)

αα-Hub domains and intrinsically disordered proteins: A decisive combo
por: Bugge, Katrine, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_f34gtbgd9obe9tqnl57mm09utu