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Absence of microsatellite instability in extramammary Paget's disease

BACKGROUND: Deficiency of DNA mismatch repair (MMR) induces microsatellite instability (MSI). Pembrolizumab, an antibody targeting PD‐1 (an immune checkpoint inhibitor), is more effective against MMR‐deficient tumours than against MMR‐proficient tumours. The status of MMR is a useful biomarker for p...

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Detalles Bibliográficos
Autores principales:	Kashiwada‐Nakamura, K., Myangat, T. M., Kajihara, I., Kusaba, Y., Tanaka, K., Sakamoto, R., Maeda‐Otsuka, S., Yamada‐Kanazawa, S., Sawamura, S., Kanemaru, H., Nishimura, Y., Honda, N., Makino, K., Miyashita, A., Aoi, J., Igata, T., Makino, T., Masuguchi, S., Fukushima, S., Ihn, H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9060031/ https://www.ncbi.nlm.nih.gov/pubmed/35663139 http://dx.doi.org/10.1002/ski2.37

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