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What can GP data tell us about the treatment of onychomycosis in the UK?

BACKGROUND: Treatment of onychomycosis is challenging, and there is much literature on optimal treatment strategies. In contrast, information on how onychomycosis is actually treated in primary care is scarce. Information on practice is important as it can reveal much, such as, to what extent nation...

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Detalles Bibliográficos
Autores principales: Sajeed, M., Wei, L., Murdan, S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9060066/
https://www.ncbi.nlm.nih.gov/pubmed/35665209
http://dx.doi.org/10.1002/ski2.84
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author Sajeed, M.
Wei, L.
Murdan, S.
author_facet Sajeed, M.
Wei, L.
Murdan, S.
author_sort Sajeed, M.
collection PubMed
description BACKGROUND: Treatment of onychomycosis is challenging, and there is much literature on optimal treatment strategies. In contrast, information on how onychomycosis is actually treated in primary care is scarce. Information on practice is important as it can reveal much, such as, to what extent national guidelines are followed and which population groups seek/receive treatment or do not do so. OBJECTIVES: To describe the pattern of onychomycosis treatment in primary care in the UK, by patient's gender and age. METHODS: A population‐based retrospective cross‐sectional study was conducted. The Health Improvement Network (THIN) database was used to calculate incidence rates of onychomycosis in the years 2001–2017. The prescription of oral and topical anti‐fungal drugs to patients with onychomycosis was reviewed. RESULTS: THIN data showed an onychomycosis incidence rate of about 50 per 100,000. More males than females (52% vs. 48%), and more people aged 50–59 years had received treatment for onychomycosis. Oral terbinafine was the most commonly prescribed drug, followed by topical amorolfine, although terbinafine was used more commonly by men and amorolfine by women. Patients with onychomycosis were also prescribed other antifungals, including itraconazole, griseofulvin, tioconazole, ketoconazole shampoo, fluconazole and clotrimazole. A greater proportion of women, compared to men, were prescribed fluconazole. CONCLUSIONS: Onychomycosis treatment in primary care in the UK is broadly in concordance with national guidelines.
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spelling pubmed-90600662022-06-04 What can GP data tell us about the treatment of onychomycosis in the UK? Sajeed, M. Wei, L. Murdan, S. Skin Health Dis Original Articles BACKGROUND: Treatment of onychomycosis is challenging, and there is much literature on optimal treatment strategies. In contrast, information on how onychomycosis is actually treated in primary care is scarce. Information on practice is important as it can reveal much, such as, to what extent national guidelines are followed and which population groups seek/receive treatment or do not do so. OBJECTIVES: To describe the pattern of onychomycosis treatment in primary care in the UK, by patient's gender and age. METHODS: A population‐based retrospective cross‐sectional study was conducted. The Health Improvement Network (THIN) database was used to calculate incidence rates of onychomycosis in the years 2001–2017. The prescription of oral and topical anti‐fungal drugs to patients with onychomycosis was reviewed. RESULTS: THIN data showed an onychomycosis incidence rate of about 50 per 100,000. More males than females (52% vs. 48%), and more people aged 50–59 years had received treatment for onychomycosis. Oral terbinafine was the most commonly prescribed drug, followed by topical amorolfine, although terbinafine was used more commonly by men and amorolfine by women. Patients with onychomycosis were also prescribed other antifungals, including itraconazole, griseofulvin, tioconazole, ketoconazole shampoo, fluconazole and clotrimazole. A greater proportion of women, compared to men, were prescribed fluconazole. CONCLUSIONS: Onychomycosis treatment in primary care in the UK is broadly in concordance with national guidelines. John Wiley and Sons Inc. 2021-12-16 /pmc/articles/PMC9060066/ /pubmed/35665209 http://dx.doi.org/10.1002/ski2.84 Text en © 2021 The Authors. Skin Health and Disease published by John Wiley & Sons Ltd on behalf of British Association of Dermatologists. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Articles
Sajeed, M.
Wei, L.
Murdan, S.
What can GP data tell us about the treatment of onychomycosis in the UK?
title What can GP data tell us about the treatment of onychomycosis in the UK?
title_full What can GP data tell us about the treatment of onychomycosis in the UK?
title_fullStr What can GP data tell us about the treatment of onychomycosis in the UK?
title_full_unstemmed What can GP data tell us about the treatment of onychomycosis in the UK?
title_short What can GP data tell us about the treatment of onychomycosis in the UK?
title_sort what can gp data tell us about the treatment of onychomycosis in the uk?
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9060066/
https://www.ncbi.nlm.nih.gov/pubmed/35665209
http://dx.doi.org/10.1002/ski2.84
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