A re‐innervated in vitro skin model of non‐histaminergic itch and skin neurogenic inflammation: PAR2‐, TRPV1‐ and TRPA1‐agonist induced functionality

BACKGROUND: Skin, and epidermis, is innervated by sensory nerve fibres. Interactions between them and signal transduction are only partially elucidated in physiological/pathological conditions, especially in pruritus. OBJECTIVES: To study the mechanisms involved in pruritus in vitro, we developed a...

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Detalles Bibliográficos
Autores principales: Lebonvallet, N., Fluhr, J. W., Le Gall‐Ianotto, C., Leschiera, R., Talagas, M., Reux, A., Bataille, A., Brun, C., Oddos, T., Pennec, J.‐P., Carré, J.‐L., Misery, L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9060135/
https://www.ncbi.nlm.nih.gov/pubmed/35663777
http://dx.doi.org/10.1002/ski2.66

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