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Preclinical assessment of dual CYP26[A1/B1] inhibitor, DX308, as an improved treatment for keratinization disorders
BACKGROUND: Retinoid‐based therapies are commonly used in the treatment of disorders of keratinization and other skin disorders but can result in non‐specific effects and adverse reactions. Use of retinoic acid metabolism blocking agents (RAMBAs) such as DX308 may address these shortcomings. OBJECTI...
Autores principales: | Veit, J.G.S., Poumay, Y., Mendes, D., Kreitinger, J., Walker, L., Paquet, A., Menigot, C., Zolezzi, F., Paller, A.S., Diaz, P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9060145/ https://www.ncbi.nlm.nih.gov/pubmed/35664983 http://dx.doi.org/10.1002/ski2.22 |
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