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Reporte de caso de síndrome de Guillain-Barré posterior a la vacuna COVID BNT162b2 mRNA

Introduction: Guillain-Barré syndrome (GBS) is a rare immune disorder that affects peripheral nerves and the cause is not known completely, but it is associated with infections by viruses or bacteria. Case report: We report the case of a 23-year-old male patient, a health student, who start 24 hours...

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Detalles Bibliográficos
Autores principales: Sosa-Hernández, Oscar, Sánchez-Cardoza, Sofía
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier España, S.L.U. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9060258/
https://www.ncbi.nlm.nih.gov/pubmed/35528113
http://dx.doi.org/10.1016/j.vacun.2022.02.002
Descripción
Sumario:Introduction: Guillain-Barré syndrome (GBS) is a rare immune disorder that affects peripheral nerves and the cause is not known completely, but it is associated with infections by viruses or bacteria. Case report: We report the case of a 23-year-old male patient, a health student, who start 24 hours after received the second dose of COVID-19 vaccine, with proximal weakness of the right upper limb, later on the left side with descending and distal progression. Discussion: GBS cases related to COVID-19 vaccines have been published, the most common being BNT162b2, which is mRNA, there are also cases published after the AZD1222 (ChAdOx1) vaccine, which is a non-replicating viral vector. The incidence of GBS is estimated at 0.43 per 100.00 doses applied, under registered national incidence of 1.1-1.8 per 100,000 persons per year. Conclusions: It is important to mention that although GBS can occur after vaccination against COVID-19, this incidence is much lower than which occurs in the community in Mexico associated with other diseases, considering more common the presence of cases related to infectious gastrointestinal diseases.