Early post-infection treatment of SARS-CoV-2 infected macaques with human convalescent plasma with high neutralizing activity had no antiviral effects but moderately reduced lung inflammation

Early in the SARS-CoV-2 pandemic, there was a high level of optimism based on observational studies and small controlled trials that treating hospitalized patients with convalescent plasma from COVID-19 survivors (CCP) would be an important immunotherapy. However, as more data from controlled trials...

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Detalles Bibliográficos
Autores principales: Van Rompay, Koen K. A., Olstad, Katherine J., Sammak, Rebecca L., Dutra, Joseph, Watanabe, Jennifer K., Usachenko, Jodie L., Immareddy, Ramya, Roh, Jamin W., Verma, Anil, Shaan Lakshmanappa, Yashavanth, Schmidt, Brian A., Di Germanio, Clara, Rizvi, Nabeela, Liu, Hongwei, Ma, Zhong-Min, Stone, Mars, Simmons, Graham, Dumont, Larry J., Allen, A. Mark, Lockwood, Sarah, Pollard, Rachel E., Ramiro de Assis, Rafael, Yee, JoAnn L., Nham, Peter B., Ardeshir, Amir, Deere, Jesse D., Jain, Aarti, Felgner, Philip L., Coffey, Lark L., Iyer, Smita S., Hartigan-O’Connor, Dennis J., Busch, Michael P., Reader, J. Rachel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9060337/
https://www.ncbi.nlm.nih.gov/pubmed/35443018
http://dx.doi.org/10.1371/journal.ppat.1009925

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