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Systems genetics in the rat HXB/BXH family identifies Tti2 as a pleiotropic quantitative trait gene for adult hippocampal neurogenesis and serum glucose

Neurogenesis in the adult hippocampus contributes to learning and memory in the healthy brain but is dysregulated in metabolic and neurodegenerative diseases. The molecular relationships between neural stem cell activity, adult neurogenesis, and global metabolism are largely unknown. Here we applied...

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Detalles Bibliográficos
Autores principales: Senko, Anna N., Overall, Rupert W., Silhavy, Jan, Mlejnek, Petr, Malínská, Hana, Hüttl, Martina, Marková, Irena, Fabel, Klaus S., Lu, Lu, Stuchlik, Ales, Williams, Robert W., Pravenec, Michal, Kempermann, Gerd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9060359/
https://www.ncbi.nlm.nih.gov/pubmed/35377872
http://dx.doi.org/10.1371/journal.pgen.1009638

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