Predicting the functional impact of KCNQ1 variants with artificial neural networks

Recent advances in experimental and computational protein structure determination have provided access to high-quality structures for most human proteins and mutants thereof. However, linking changes in structure in protein mutants to functional impact remains an active area of method development. I...

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Detalles Bibliográficos
Autores principales: Phul, Saksham, Kuenze, Georg, Vanoye, Carlos G., Sanders, Charles R., George, Alfred L., Meiler, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9060377/
https://www.ncbi.nlm.nih.gov/pubmed/35442947
http://dx.doi.org/10.1371/journal.pcbi.1010038

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9060377/
https://www.ncbi.nlm.nih.gov/pubmed/35442947
http://dx.doi.org/10.1371/journal.pcbi.1010038

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