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Formation of clustered DNA damage in vivo upon irradiation with ionizing radiation: Visualization and analysis with atomic force microscopy

Clustered DNA damage is related to the biological effects of ionizing radiation. However, its precise yield and complexity (i.e., number of lesions per damaged site) in vivo remain unknown. To better understand the consequences of clustered DNA damage, a method was established to evaluate its yield...

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Detalles Bibliográficos
Autores principales: Nakano, Toshiaki, Akamatsu, Ken, Tsuda, Masataka, Tujimoto, Ayane, Hirayama, Ryoichi, Hiromoto, Takeshi, Tamada, Taro, Ide, Hiroshi, Shikazono, Naoya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9060515/
https://www.ncbi.nlm.nih.gov/pubmed/35324325
http://dx.doi.org/10.1073/pnas.2119132119