Development of a biosensor assessing SARS-CoV-2 main protease proteolytic activity in living cells for antiviral drugs screening

• The biosensor reported in our study can monitor SARS-CoV-2 M(pro) activity in living cells instead of in vitro solutions. • The biosensor reported in our study is sensitive and easy to operate. • It is suitable for high-throughput screening. • It has the potential to be used in small animal models...

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Detalles Bibliográficos
Autores principales: Zhang, Yuan, Li, Chunjie, Ke, Xianliang, Luo, Dan, Liu, Yan, Chen, Quanjiao, Wang, Hanzhong, Song, Xiaohui, Zheng, Zhenhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wuhan Institute of Virology, Chinese Academy of Sciences 2022
Materias:
Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9060717/
https://www.ncbi.nlm.nih.gov/pubmed/35513272
http://dx.doi.org/10.1016/j.virs.2022.04.002

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