Copper-catalyzed cross-dehydrogenative coupling between quinazoline-3-oxides and indoles

A novel and simple protocol for the synthesis of 4-(indole-3-yl)quinazolines via cross-dehydrogenative coupling of quinazoline-3-oxides and indoles under an air atmosphere has been developed. A series of biheteroaryl products were obtained in moderate to good yields.

Detalles Bibliográficos
Autores principales: Yang, Qin, Yin, Zhijian, Zheng, Lifang, Yuan, Jianjun, Wei, Song, Ding, Qiuping, Peng, Yiyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9060877/
https://www.ncbi.nlm.nih.gov/pubmed/35517267
http://dx.doi.org/10.1039/c8ra09864f
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author Yang, Qin
Yin, Zhijian
Zheng, Lifang
Yuan, Jianjun
Wei, Song
Ding, Qiuping
Peng, Yiyuan
author_facet Yang, Qin
Yin, Zhijian
Zheng, Lifang
Yuan, Jianjun
Wei, Song
Ding, Qiuping
Peng, Yiyuan
author_sort Yang, Qin
collection PubMed
description A novel and simple protocol for the synthesis of 4-(indole-3-yl)quinazolines via cross-dehydrogenative coupling of quinazoline-3-oxides and indoles under an air atmosphere has been developed. A series of biheteroaryl products were obtained in moderate to good yields.
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spelling pubmed-90608772022-05-04 Copper-catalyzed cross-dehydrogenative coupling between quinazoline-3-oxides and indoles Yang, Qin Yin, Zhijian Zheng, Lifang Yuan, Jianjun Wei, Song Ding, Qiuping Peng, Yiyuan RSC Adv Chemistry A novel and simple protocol for the synthesis of 4-(indole-3-yl)quinazolines via cross-dehydrogenative coupling of quinazoline-3-oxides and indoles under an air atmosphere has been developed. A series of biheteroaryl products were obtained in moderate to good yields. The Royal Society of Chemistry 2019-02-18 /pmc/articles/PMC9060877/ /pubmed/35517267 http://dx.doi.org/10.1039/c8ra09864f Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Chemistry
Yang, Qin
Yin, Zhijian
Zheng, Lifang
Yuan, Jianjun
Wei, Song
Ding, Qiuping
Peng, Yiyuan
Copper-catalyzed cross-dehydrogenative coupling between quinazoline-3-oxides and indoles
title Copper-catalyzed cross-dehydrogenative coupling between quinazoline-3-oxides and indoles
title_full Copper-catalyzed cross-dehydrogenative coupling between quinazoline-3-oxides and indoles
title_fullStr Copper-catalyzed cross-dehydrogenative coupling between quinazoline-3-oxides and indoles
title_full_unstemmed Copper-catalyzed cross-dehydrogenative coupling between quinazoline-3-oxides and indoles
title_short Copper-catalyzed cross-dehydrogenative coupling between quinazoline-3-oxides and indoles
title_sort copper-catalyzed cross-dehydrogenative coupling between quinazoline-3-oxides and indoles
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9060877/
https://www.ncbi.nlm.nih.gov/pubmed/35517267
http://dx.doi.org/10.1039/c8ra09864f
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