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It Takes Two to Tango: Combining Conventional Culture With Molecular Diagnostics Enhances Accuracy of Streptococcus pneumoniae Detection and Pneumococcal Serogroup/Serotype Determination in Carriage
BACKGROUND: The specificity of molecular methods for the detection of Streptococcus pneumoniae carriage is under debate. We propose a procedure for carriage surveillance and vaccine impact studies that increases the accuracy of molecular detection of live pneumococci in polymicrobial respiratory sam...
Autores principales: | Miellet, Willem R., van Veldhuizen, Janieke, Litt, David, Mariman, Rob, Wijmenga-Monsuur, Alienke J., Badoux, Paul, Nieuwenhuijsen, Tessa, Thombre, Rebecca, Mayet, Sanaa, Eletu, Seyi, Sheppard, Carmen, van Houten, Marianne Alice, Rots, Nynke Y., Miller, Elizabeth, Fry, Norman K., Sanders, Elisabeth A. M., Trzciński, Krzysztof |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9060910/ https://www.ncbi.nlm.nih.gov/pubmed/35509314 http://dx.doi.org/10.3389/fmicb.2022.859736 |
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