Effects of C5a and Receptor CD88 on Glutamate and N-Methyl-D-Aspartic Acid Receptor Expression in the Mouse Model of Optic Neuromyelitis

OBJECTIVE: To analyze the role of C5a, C5a receptor (CD88), glutamic acid, and N-methyl-D-aspartic acid receptors (NMDAR1 and NMDAR2B) in the onset of neuromyelitis optica (NMO) disease in mice. METHOD: To select C57BL/6 wild-type (WT) mice and C5a receptor gene knockout (C5aR-/-) mice, use NMO-IgG...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Ling, Tang, Jiangwei, Wang, Hongxin, Liu, Jiamei, Zhou, Lina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9061005/
https://www.ncbi.nlm.nih.gov/pubmed/35509858
http://dx.doi.org/10.1155/2022/4997393

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9061005/
https://www.ncbi.nlm.nih.gov/pubmed/35509858
http://dx.doi.org/10.1155/2022/4997393

Ejemplares similares