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COVID-19 vaccines in pregnancy

COVID-19 caused by SARS-CoV-2 coronavirus has been associated with severe illness in pregnant women. Furthermore, COVID-19 during pregnancy is associated with adverse fetal outcomes including preterm labor. Pregnant women were largely excluded from initial clinical trials investigating the safety an...

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Detalles Bibliográficos
Autores principales: Nunes, Marta C., Madhi, Shabir A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9061132/
https://www.ncbi.nlm.nih.gov/pubmed/35610123
http://dx.doi.org/10.1016/j.molmed.2022.04.012
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author Nunes, Marta C.
Madhi, Shabir A.
author_facet Nunes, Marta C.
Madhi, Shabir A.
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description COVID-19 caused by SARS-CoV-2 coronavirus has been associated with severe illness in pregnant women. Furthermore, COVID-19 during pregnancy is associated with adverse fetal outcomes including preterm labor. Pregnant women were largely excluded from initial clinical trials investigating the safety and efficacy of COVID-19 vaccines; however, they have since been included as part of the routine roll-out of these vaccines. This narrative review synthesizes the evidence on the safety, immunogenicity, and effectiveness predominantly of the mRNA COVID-19 vaccines which have been most widely used in pregnant women.
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spelling pubmed-90611322022-05-03 COVID-19 vaccines in pregnancy Nunes, Marta C. Madhi, Shabir A. Trends Mol Med Review COVID-19 caused by SARS-CoV-2 coronavirus has been associated with severe illness in pregnant women. Furthermore, COVID-19 during pregnancy is associated with adverse fetal outcomes including preterm labor. Pregnant women were largely excluded from initial clinical trials investigating the safety and efficacy of COVID-19 vaccines; however, they have since been included as part of the routine roll-out of these vaccines. This narrative review synthesizes the evidence on the safety, immunogenicity, and effectiveness predominantly of the mRNA COVID-19 vaccines which have been most widely used in pregnant women. Elsevier Ltd. 2022-08 2022-05-03 /pmc/articles/PMC9061132/ /pubmed/35610123 http://dx.doi.org/10.1016/j.molmed.2022.04.012 Text en © 2022 Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Review
Nunes, Marta C.
Madhi, Shabir A.
COVID-19 vaccines in pregnancy
title COVID-19 vaccines in pregnancy
title_full COVID-19 vaccines in pregnancy
title_fullStr COVID-19 vaccines in pregnancy
title_full_unstemmed COVID-19 vaccines in pregnancy
title_short COVID-19 vaccines in pregnancy
title_sort covid-19 vaccines in pregnancy
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9061132/
https://www.ncbi.nlm.nih.gov/pubmed/35610123
http://dx.doi.org/10.1016/j.molmed.2022.04.012
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