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Design and synthesis of cysteine-specific labels for photo-crosslinking studies

Chemical cross-linking mass-spectrometry (XL-MS) represents a powerful methodology to map ligand/biomacromolecule interactions, particularly where conventional methods such as X-ray crystallography, nuclear magnetic resonance (NMR) spectroscopy or cryo-electron microscopy (EM) are not feasible. In t...

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Detalles Bibliográficos
Autores principales: Walko, Martin, Hewitt, Eric, Radford, Sheena E., Wilson, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9061181/
https://www.ncbi.nlm.nih.gov/pubmed/35521201
http://dx.doi.org/10.1039/c8ra10436k