IPO11 regulates the nuclear import of BZW1/2 and is necessary for AML cells and stem cells

AML cells are arranged in a hierarchy with stem/progenitor cells giving rise to more differentiated bulk cells. Despite the importance of stem/progenitors in the pathogenesis of AML, the determinants of the AML stem/progenitor state are not fully understood. Through a comparison of genes that are si...

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Detalles Bibliográficos
Autores principales: Nachmias, Boaz, Khan, Dilshad H., Voisin, Veronique, Mer, Arvind S., Thomas, Geethu Emily, Segev, Nadav, St-Germain, Jonathan, Hurren, Rose, Gronda, Marcela, Botham, Aaron, Wang, Xiaoming, Maclean, Neil, Seneviratne, Ayesh K., Duong, Nathan, Xu, Changjiang, Arruda, Andrea, Orouji, Elias, Algouneh, Arash, Hakem, Razqallah, Shlush, Liran, Minden, Mark D., Raught, Brian, Bader, Gary D., Schimmer, Aaron D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9061300/
https://www.ncbi.nlm.nih.gov/pubmed/35152270
http://dx.doi.org/10.1038/s41375-022-01513-4

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