RIP140 inhibits glycolysis-dependent proliferation of breast cancer cells by regulating GLUT3 expression through transcriptional crosstalk between hypoxia induced factor and p53

Glycolysis is essential to support cancer cell proliferation, even in the presence of oxygen. The transcriptional co-regulator RIP140 represses the activity of transcription factors that drive cell proliferation and metabolism and plays a role in mammary tumorigenesis. Here we use cell proliferation...

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Detalles Bibliográficos
Autores principales: Jacquier, Valentin, Gitenay, Delphine, Fritsch, Samuel, Bonnet, Sandrine, Győrffy, Balázs, Jalaguier, Stéphan, Linares, Laetitia K., Cavaillès, Vincent, Teyssier, Catherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9061696/
https://www.ncbi.nlm.nih.gov/pubmed/35501580
http://dx.doi.org/10.1007/s00018-022-04277-3

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