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Hypomethylating agent and venetoclax with FLT3 inhibitor “triplet” therapy in older/unfit patients with FLT3 mutated AML
In older/unfit newly diagnosed patients with FLT3 mutated acute myeloid leukemia (AML), lower intensity chemotherapy (LIC) in combination with either a FLT3 inhibitor or with venetoclax results in poor overall survival (median 8 to 12.5 months). We performed a retrospective analysis of 87 newly diag...
Autores principales: | Yilmaz, Musa, Kantarjian, Hagop, Short, Nicholas J., Reville, Patrick, Konopleva, Marina, Kadia, Tapan, DiNardo, Courtney, Borthakur, Gautam, Pemmaraju, Naveen, Maiti, Abhishek, Jabbour, Elias, Jain, Nitin, Issa, Ghayas, Takahashi, Koichi, Sasaki, Koji, Ohanian, Maro, Pierce, Sherry, Tang, Guillin, Loghavi, Sanam, Patel, Keyur, Wang, Sa A., Garcia-Manero, Guillermo, Andreeff, Michael, Ravandi, Farhad, Daver, Naval |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9061716/ https://www.ncbi.nlm.nih.gov/pubmed/35501304 http://dx.doi.org/10.1038/s41408-022-00670-0 |
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