Unique binding pattern for a lineage of human antibodies with broad reactivity against influenza A virus

Most structurally characterized broadly neutralizing antibodies (bnAbs) against influenza A viruses (IAVs) target the conserved conformational epitopes of hemagglutinin (HA). Here, we report a lineage of naturally occurring human antibodies sharing the same germline gene, V(H)3-48/V(K)1-12. These an...

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Detalles Bibliográficos
Autores principales: Sun, Xiaoyu, Liu, Caixuan, Lu, Xiao, Ling, Zhiyang, Yi, Chunyan, Zhang, Zhen, Li, Zi, Jin, Mingliang, Wang, Wenshuai, Tang, Shubing, Wang, Fangfang, Wang, Fang, Wangmo, Sonam, Chen, Shuangfeng, Li, Li, Ma, Liyan, Zhang, Yaguang, Yang, Zhuo, Dong, Xiaoping, Qian, Zhikang, Ding, Jianping, Wang, Dayan, Cong, Yao, Sun, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9061721/
https://www.ncbi.nlm.nih.gov/pubmed/35501328
http://dx.doi.org/10.1038/s41467-022-29950-w

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