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The myokine Fibcd1 is an endogenous determinant of myofiber size and mitigates cancer-induced myofiber atrophy
Decline in skeletal muscle cell size (myofiber atrophy) is a key feature of cancer-induced wasting (cachexia). In particular, atrophy of the diaphragm, the major muscle responsible for breathing, is an important determinant of cancer-associated mortality. However, therapeutic options are limited. He...
Autores principales: | Graca, Flavia A., Rai, Mamta, Hunt, Liam C., Stephan, Anna, Wang, Yong-Dong, Gordon, Brittney, Wang, Ruishan, Quarato, Giovanni, Xu, Beisi, Fan, Yiping, Labelle, Myriam, Demontis, Fabio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9061726/ https://www.ncbi.nlm.nih.gov/pubmed/35501350 http://dx.doi.org/10.1038/s41467-022-30120-1 |
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