Mre11-Rad50 oligomerization promotes DNA double-strand break repair

The conserved Mre11-Rad50 complex is crucial for the detection, signaling, end tethering and processing of DNA double-strand breaks. While it is known that Mre11-Rad50 foci formation at DNA lesions accompanies repair, the underlying molecular assembly mechanisms and functional implications remained...

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Detalles Bibliográficos
Autores principales: Kissling, Vera M., Reginato, Giordano, Bianco, Eliana, Kasaciunaite, Kristina, Tilma, Janny, Cereghetti, Gea, Schindler, Natalie, Lee, Sung Sik, Guérois, Raphaël, Luke, Brian, Seidel, Ralf, Cejka, Petr, Peter, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9061753/
https://www.ncbi.nlm.nih.gov/pubmed/35501303
http://dx.doi.org/10.1038/s41467-022-29841-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9061753/
https://www.ncbi.nlm.nih.gov/pubmed/35501303
http://dx.doi.org/10.1038/s41467-022-29841-0

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