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N(6)-methyladenosine (m(6)A) methyltransferase METTL3-mediated LINC00680 accelerates osteoarthritis through m(6)A/SIRT1 manner

Increasing evidence suggest the biological roles of N(6)-methyladenosine (m(6)A) and long noncoding RNAs (lncRNAs) in the bone disease, especially osteoarthritis (OA). However, the interaction of m(6)A and lncRNA in osteoarthritis is still unclear. Here, we found that a m(6)A-related lncRNA LINC0068...

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Detalles Bibliográficos
Autores principales: Ren, Jiangdong, Li, Yicheng, Wuermanbieke, Shalitanati, Hu, Shu, Huang, Guangxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9061755/
https://www.ncbi.nlm.nih.gov/pubmed/35501316
http://dx.doi.org/10.1038/s41420-022-00890-0

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