Comparative metabolomic analysis in plasma and cerebrospinal fluid of humans and in plasma and brain of mice following antidepressant-dose ketamine administration

Subanesthetic-dose racemic (R,S)-ketamine (ketamine) produces rapid, robust, and sustained antidepressant effects in major depressive disorder (MDD) and bipolar disorder (BD) and has also been shown to effectively treat neuropathic pain, complex regional pain syndrome, and post-traumatic stress diso...

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Detalles Bibliográficos
Autores principales: Moaddel, Ruin, Zanos, Panos, Farmer, Cristan A., Kadriu, Bashkim, Morris, Patrick J., Lovett, Jacqueline, Acevedo-Diaz, Elia E., Cavanaugh, Grace W., Yuan, Peixiong, Yavi, Mani, Thomas, Craig J., Park, Lawrence T., Ferrucci, Luigi, Gould, Todd D., Zarate, Carlos A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9061764/
https://www.ncbi.nlm.nih.gov/pubmed/35501309
http://dx.doi.org/10.1038/s41398-022-01941-x

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