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L3MBTL2-mediated CGA transcriptional suppression promotes pancreatic cancer progression through modulating autophagy

L3MBTL2 is a crucial component of ncPRC1.6 and has been implicated in transcriptional repression and chromatin compaction. However, the repression mechanism of L3MBTL2 and its biological functions are largely undefined. Here, we found that L3MBTL2 plays a distinct oncogenic role in tumor development...

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Detalles Bibliográficos
Autores principales:	Huang, Hua, Pan, Ruining, Zhao, Yue, Li, Huan, Zhu, Huiyu, Wang, Sijia, Khan, Aamir Ali, Wang, Juan, Liu, Xinhui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9061862/ https://www.ncbi.nlm.nih.gov/pubmed/35521536 http://dx.doi.org/10.1016/j.isci.2022.104249

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