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Synthesis of C4-alkynylisoxazoles via a Pd-catalyzed Sonogashira cross-coupling reaction

A Pd-catalyzed Sonogashira cross-coupling reaction for the synthesis of C4-alkynylisoxazoles from 3,5-disubsitituted-4-iodoisoxazoles and terminal alkynes was described, which could afford the corresponding products with high yield (up to 98%). The results indicated that the steric effect from the g...

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Detalles Bibliográficos
Autores principales:	Yang, Wen, Yao, Yongqi, Yang, Xin, Deng, Yingying, Lin, Qifu, Yang, Dingqiao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2019
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9061866/ https://www.ncbi.nlm.nih.gov/pubmed/35517684 http://dx.doi.org/10.1039/c9ra00577c

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