In Transgenic Erythropoietin Deficient Mice, an Increase in Respiratory Response to Hypercapnia Parallels Abnormal Distribution of CO(2)/H(+)-Activated Cells in the Medulla Oblongata

Erythropoietin (Epo) and its receptor are expressed in central respiratory areas. We hypothesized that chronic Epo deficiency alters functioning of central respiratory areas and thus the respiratory adaptation to hypercapnia. The hypercapnic ventilatory response (HcVR) was evaluated by whole body pl...

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Detalles Bibliográficos
Autores principales: Jeton, Florine, Perrin-Terrin, Anne-Sophie, Yegen, Celine-Hivda, Marchant, Dominique, Richalet, Jean-Paul, Pichon, Aurélien, Boncoeur, Emilie, Bodineau, Laurence, Voituron, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9061944/
https://www.ncbi.nlm.nih.gov/pubmed/35514353
http://dx.doi.org/10.3389/fphys.2022.850418

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