Targeting the N-Terminus Domain of the Coronavirus Nucleocapsid Protein Induces Abnormal Oligomerization via Allosteric Modulation

Epidemics caused by coronaviruses (CoVs), namely the severe acute respiratory syndrome (SARS) (2003), Middle East respiratory syndrome (MERS) (2012), and coronavirus disease 2019 (COVID-19) (2019), have triggered a global public health emergency. Drug development against CoVs is inherently arduous....

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Detalles Bibliográficos
Autores principales: Hsu, Jia-Ning, Chen, Jyun-Siao, Lin, Shan-Meng, Hong, Jhen-Yi, Chen, Yi-Jheng, Jeng, U-Ser, Luo, Shun-Yuan, Hou, Ming-Hon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9061996/
https://www.ncbi.nlm.nih.gov/pubmed/35517857
http://dx.doi.org/10.3389/fmolb.2022.871499

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9061996/
https://www.ncbi.nlm.nih.gov/pubmed/35517857
http://dx.doi.org/10.3389/fmolb.2022.871499

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