Synthesis of d-glyco-alkynone derivatives via carbonylative Sonogashira reaction

A carbonylative Sonogashira coupling approach to the synthesis of glyco-alkynones is described. Eighteen examples were obtained in moderate do nearly quantitative yields under mild conditions employing Mo(CO)(6) as a safe carbon monoxide source. Functionalization of the alkynyl moiety via cycloaddit...

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Autores principales: Darbem, Mariana P., Esteves, C. Henrique A., de Oliveira, Isadora M., Reis, Joel S., Pimenta, Daniel C., Stefani, Hélio A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9062118/
https://www.ncbi.nlm.nih.gov/pubmed/35520747
http://dx.doi.org/10.1039/c9ra00523d
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author Darbem, Mariana P.
Esteves, C. Henrique A.
de Oliveira, Isadora M.
Reis, Joel S.
Pimenta, Daniel C.
Stefani, Hélio A.
author_facet Darbem, Mariana P.
Esteves, C. Henrique A.
de Oliveira, Isadora M.
Reis, Joel S.
Pimenta, Daniel C.
Stefani, Hélio A.
author_sort Darbem, Mariana P.
collection PubMed
description A carbonylative Sonogashira coupling approach to the synthesis of glyco-alkynones is described. Eighteen examples were obtained in moderate do nearly quantitative yields under mild conditions employing Mo(CO)(6) as a safe carbon monoxide source. Functionalization of the alkynyl moiety via cycloaddition with organic azides provided six examples of glyco-triazoles.
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spelling pubmed-90621182022-05-04 Synthesis of d-glyco-alkynone derivatives via carbonylative Sonogashira reaction Darbem, Mariana P. Esteves, C. Henrique A. de Oliveira, Isadora M. Reis, Joel S. Pimenta, Daniel C. Stefani, Hélio A. RSC Adv Chemistry A carbonylative Sonogashira coupling approach to the synthesis of glyco-alkynones is described. Eighteen examples were obtained in moderate do nearly quantitative yields under mild conditions employing Mo(CO)(6) as a safe carbon monoxide source. Functionalization of the alkynyl moiety via cycloaddition with organic azides provided six examples of glyco-triazoles. The Royal Society of Chemistry 2019-03-25 /pmc/articles/PMC9062118/ /pubmed/35520747 http://dx.doi.org/10.1039/c9ra00523d Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Chemistry
Darbem, Mariana P.
Esteves, C. Henrique A.
de Oliveira, Isadora M.
Reis, Joel S.
Pimenta, Daniel C.
Stefani, Hélio A.
Synthesis of d-glyco-alkynone derivatives via carbonylative Sonogashira reaction
title Synthesis of d-glyco-alkynone derivatives via carbonylative Sonogashira reaction
title_full Synthesis of d-glyco-alkynone derivatives via carbonylative Sonogashira reaction
title_fullStr Synthesis of d-glyco-alkynone derivatives via carbonylative Sonogashira reaction
title_full_unstemmed Synthesis of d-glyco-alkynone derivatives via carbonylative Sonogashira reaction
title_short Synthesis of d-glyco-alkynone derivatives via carbonylative Sonogashira reaction
title_sort synthesis of d-glyco-alkynone derivatives via carbonylative sonogashira reaction
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9062118/
https://www.ncbi.nlm.nih.gov/pubmed/35520747
http://dx.doi.org/10.1039/c9ra00523d
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